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I-Analgesia Ye-Snake Venom Powder Omisiwe Omisiwe Isithombe Esifakiwe
  • I-Analgesia Ye-Snake Venom Powder Omisiwe Omisiwe
  • I-Analgesia Ye-Snake Venom Powder Omisiwe Omisiwe
  • I-Analgesia Ye-Snake Venom Powder Omisiwe Omisiwe

I-Analgesia Ye-Snake Venom Powder Omisiwe Omisiwe

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Ukusetshenziswa kobuhlungu benyoka ku-agkistrodon (inyoka enezinyathelo ezinhlanu): i-analgesia
Ubuthi benyoka bunomsebenzi wokuxosha umoya nokususa umswakama, i-anticoagulation kanye ne-antithrombus, ukususa i-fibrinogen, ukwehlisa i-viscosity yegazi, ukunweba imithambo yegazi, ukuthuthukisa i-microcirculation kanye nokwehlisa i-lipids yegazi.Ubuthi be-agkistrodon agkistrodon bunevelu yokwelapha ephezulu, equkethe izingxenye zekhemisi ezikhuthaza ukuhlangana, i-fibrinolysis, ukulwa nomdlavuza kanye ne-analgesia.Imisebenzi esemqoka yilezi:
1. I-analgesia.
2. Umfutho wegazi ophansi.
3. I-Hemostasis kanye ne-anticoagulation.
4. umphumela wokulwa nomdlavuza.
5. ukwelashwa kwe-cerebral thrombosis kanye ne-vasculitis.
6. Yelapha izilonda zesisu kanye ne-duodenal.
7. iyi-serum elwa negazi.
8. Ukuba umlutha wezempi nezidakamizwa

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

I-analgesia

Eminyakeni yamuva, ucwaningo oluvela esifundeni eningizimu ye-anhui eside noded pit viper, i-viper kanye nemfezi ukuhlanzwa kokumelana nezidakamizwa ongahluziwe high coagulation state enzyme, amaprotheni C activation (PCA) kanye izinto ezihlukahlukene bioactive, izifundo zokuhlola ukuqinisekisile ukuthi isithako esisebenzayo singathinta inqubo ye-coagulation, sithinte ukunamathela kweplatelet, ukuhlanganisa kanye nokuvikela ukusebenza kwe-vascular endothelial cell, ngempumelelo ephezulu, i-anticoagulation, umphumela we-thrombolysis, Kubaluleke kakhulu ekuvimbeleni nasekwelapheni izifo ze-thrombotic emitholampilo kanye nokuthuthukiswa kwe-hypercoagulability yegazi. .Kuphinde kwatholakala ukuthi i-SNAKE poison PCA ingabulala ngokuqondile amaseli e-leukemia angu-K562 futhi ivimbele ukumetastasis kwamangqamuzana omdlavuza, futhi amathuba okusebenza kwawo emtholampilo abanzi kakhulu.Ilabhorethri kufanele ithathe futhi iqedele isikhwama kazwelonke sesayensi yemvelo kanye nomnyango wezempilo kanye nezimali zocwaningo lwesayensi ehhovisi lezempilo lesifundazwe sase-anhui, uMnyango wezeMfundo "wakhomba ukuqabula ubuthi benyoka kubangela umshini we-DIC", "wakhomba ukuqabula inyoka ezilwaneni imbangela ukopha indlela yokucwaninga", "i-enzyme indlela ejwayelekile yokuxilongwa kwesilonda senyoka kanye nokuxilongwa okuhlukile kwemindeni yayo yezinyoka" nokunye okuningi kwezihloko zocwaningo;Amaphrojekthi amanje ahlanganisa: "Ucwaningo ngokungabikho kweprotheyini ye-anticoagulant ye-hemorrhagic e-Pentaphylla pentaphylla", "Ucwaningo mayelana nendlela yamangqamuzana yomphumela we-PCA ekusebenzeni kwe-vascular endothelial ye-Ankistrodon agkistrodon venom", "Funda nge-molecular biology ye-PCA antitumor cells. ku-Snake Venom", kanye nokuhlukaniswa nokuhlanzwa kwezingxenye ze-neuroanalgesic ku-Cobra venom.

Ngo-1976, i-Kunming Institute of Zoology, esifundazweni sase-Yunnan yathuthukisa ngempumelelo i- "Ketongling" kusuka ebuhlungwini benyoka yokwelashwa kwezifo ezihlukahlukene ezibuhlungu, futhi yazuza umphumela oyingqayizivele we-analgesic.I-Cao Yisheng ithuthukise "i-Compound Ketongning" ekwelapheni ubuhlungu be-neuropathic, ubuhlungu bomdlavuza kanye nokulutha izidakamizwa kubonise umphumela omuhle kakhulu.Ngenxa yomsebenzi wayo ophezulu we-analgesic kanye nokungewona umlutha, izidakamizwa zokuqeda ubuhlungu benyoka zisetshenziswa ngokomtholampilo ukuze zimiselele i-morphine ekwelapheni ubuhlungu bomdlavuza wesigaba sekwephuzile.

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