Ingxenye entsha ye-AA-MP-I yahlukaniswa ne-Agkistrodon acutus venom nge-thiophilic chromatography, i-Sephadex G-75, ijeli eluhlaza okwesibhakabhaka kanye ne-POROS HQ 20 ion exchange chromatography.I-enzyme iyiphrotheni ye-monomer enesisindo se-molecular engu-22.9 kDa, enephuzu le-isoelectric elingu-5.55, alikho iqembu likashukela elingathathi hlangothi, futhi ukulandelana kwayo kwe-N-terminal ithi STEFQRYMEIVVDHSMVK.Imiphumela ibonisa ukuthi iyi-PI metalloproteinase entsha, ezwela ukushisa, inomsebenzi we-anticoagulant, umsebenzi onamandla we-anticoagulant ku-40 ℃, inobuthi be-hemorrhagic, futhi ayinayo i-phospholipase A: umsebenzi.
Isikhathi sokuthumela: Dec-20-2022