Ubuhlungu be-Agkistrodon acutus (ebuye yaziwe ngokuthi i-Agkistrodon acutus) bukhishwa ngokucindezela ikhala nokukhama, bese yengezwa nge-5O yomuthi we-herbal wase-Chinese ofana ne-wolfberry.Yenziwa ngokucwiliswa emanzini, ukucubungula nokuhlanza okusanhlamvu i-Baijiu.Kuhlanganiswe ku
I-Agkistrodon acutus venom inemisebenzi yokuqeda ukukhathala, ukulwa nokuguga, ukuqinisa amasosha omzimba, ukukhuthaza ukudla, ukuthuthukisa isifiso sobulili, futhi inomphumela osobala wokwelapha ekwelapheni izifo zesikhumba kanye ne-psoriasis (psoriasis). izinhlangothi zombili zekhanda nomhlathi wenyoka
Ukukhishwa kwendlala yesihlungu kumhlophe qhwa noma kumhlophe kancane okukhuthaza ukuphuma kwamazinyo anobuthi ezinhlangothini zombili zeshubhu.
Uketshezi oluphuzi lwe-viscous lungenye yezinto ezinobuthi obunamandla wokujikeleza kwegazi kubuthi bezilwane.ithiphu
Ubuthi obusha be-Agkistrodon halys bunofishi kancane, futhi izingxenye zayo ezinobuthi ziyinkimbinkimbi, ikakhulukazi ukujikeleza kwegazi.
Inobuthi [1], equkethe inkimbinkimbi ye-polypeptide nama-enzyme amaningi, i-phospholipase A Protease
Futhi i-kallikrein, njll. Ubuthi benyoka bungabangela umonakalo omkhulu ezicutshini zomuntu noma zezilwane
Ukukhubazeka nokufa.Kodwa-ke, imikhiqizo yenyoka egayiwe ingasetshenziswa njengokudla kwezempilo ekulweni nokukhathala
Ukwaneliswa ukukhathala, ukulwa nokuguga, ukuqinisa amasosha omzimba, ukukhuthaza isifiso sokudla, ukukhulisa isifiso socansi, njll.
umphumela.Ngemva kokuba ubuthi benyoka bucwiliswe ku-ethanol, ayinalo iphunga eliwufishi, amaprotheni kanye nentambo ye-cytotoxic.
Ukulahlekelwa ubuthi begazi ngeke kuholele ekuminyeneni kwezicubu, i-edema kanye ne-necrosis, kuyilapho i-phospholipase A.
I-Protease ne-kinin nazo azibangeli umzimba ukuthi ukhulule i-kinin histamine nombala ongu-5-hydroxy
Ama-amine nezinye izinto.Ngalesi sizathu, umbhali kanye nethimba locwaningo basebenzisa ubuthi be-Agkistrodon acutus njengento eyinhloko
I-Qi neminye imithi yama-herbal yaseShayina isetshenziswa njengezinto ezisizayo [2], ezicutshungulwa futhi zithuthukiswe ngemithi yesayensi yokusanhlamvu i-Baijiu.
I-Agkistrodon acutus venom (umkhiqizo omusha) enokunakekelwa kwezempilo nomthelela wokwelapha kanye nokusetshenziswa kalula
Ukufeza izidingo zemakethe kanye nezidingo zabantu zokunakekelwa kwezempilo nokwelashwa kwezifo.
1 Izinto kanye nezindlela
1.1 Impahla Ubuthi be-Agkistrodon acutus (impushana entsha ne-lyophilized) buzoba busha futhi bubukhali phakathi namahora ayi-18.
Ubuthi benyoka bekhwalithi ephezulu be-Agkistrodon halys venom kanye nempushana e-lyophilized ayinalo igazi nokungcola.Umuthi omusha we-herbal wamaShayina
I-Lycium barbarum, entsha, ngaphandle kokukhunta nokuwohloka, njll.
1.2 Izinsimbi nezinto zokusebenza KFL-1035 oral liquid sealing machine
Machinery Co., Ltd.).
1.3 Indlela (1) Chaza ubuthi obusha be-Agkistrodon acutus (impushana eqandisiwe ye-Agkistrodon acutus) emanzini angenalutho
50 (5O.) okusanhlamvu i-Baijiu yacwiliswa futhi yavalwa izinsuku ezingu-30 ukuze ihlanzwe.
(2) Geza amakhambi amaShayina amasha njenge-wolfberry, womisa amaconsi amanzi, bese wengeza u-5O.I-Grain Baijiu
Gxila ekugxilweni kwengxenye ye-1/lO izinsuku ezingu-3O (govuza kanye njalo ezinsukwini eziyi-10, vula ngaphambi kokuxuba, futhi ugovuze
Ngemuva kokuvalwa).(3) I-Baijiu ihlanzwe ngokucwilisa ubuthi be-Agkistrodon acutus
I-Baijiu ecwiliswe futhi yahlanzwa ngomuthi wendabuko waseShayina ixutshwa ngokulinganayo, ibhodlela, ikepisi, ifakwe imisebe futhi ihlanzwe, futhi ihlolwe ukuthi ifaneleke yini.
(Izinga lekhwalithi yomkhiqizo: ① Inkomba yezinzwa: I-Agkistrodon acutus venom insundu ngokukhanyayo futhi ibomvu ngohhafu
Uketshezi olucacile olucacile, oluxegayo olufana nobisi oluyi-turbid protein ongqimbeni olungezansi lungabonwa ngamehlo anqunu,
Nyakazisa kahle ngaphandle kwezinsalela zekhekhe, ukunambitheka okumnandi, iphunga elimnandi, iphunga elingavamile, ukunambitheka okumuncu kanye nesikhutha
Nambitha.② Izinkomba zomzimba namakhemikhali [: i-ethanol degree 45~48.Ukuhola (kubalwe ngu-Pb)
0.10g/kg, i-arsenic (ibalwa njenge-As) ≤ 0.5mg/kg, ithusi (ibalwa njenge-Cu) ≤ 1.0
I-Mg/kg, i-methanol ≤ O.04g/lO0ml, uwoyela wefuseli ≤ O.1/100ml, i-cyanide
I-Manganese ayitholakali.③ Inkomba ye-Microbiological: inombolo ephelele yamagciwane<1000/g, iqembu le-coliform
≤ Izingcezu ezingu-30/lOOg, amagciwane e-pathogenic awatholwanga), apakishwe njenge
Isikhathi sokuthumela: Feb-07-2023