Uhlelo lokusebenza lwe-Snake Venom Anti-cancer Umphumela wesithombe esifakiwe

I-Snake Venom Application Anti-cancer effect

Incazelo emfushane:

Impahla eluhlaza Impushana eyomile yobuthi benyoka ekhiqizwa inkampani yethu yenziwa ngobuthi obuqoqiwe be-agkistrodon.
Impushana eyomisiwe enobuhlungu benyoka isetshenziswa kakhulu kwezokwelapha, ezempi, ezobuhle neminye imikhakha.Impushana eqandisiwe yobuhlungu benyoka inobubanzi bokusebenza kanye nethemba elibanzi lokuthuthuka.

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

3 Umphumela wokulwa nomdlavuza

Ngokuthuthuka kwesayensi nobuchwepheshe, bayanda abantu asebefunde ubuthi bezinyoka
Izingxenye eziningi zodwa zinemisebenzi yokulwa nomdlavuza, futhi izindlela zazo zokwenza zingahlukaniswa kabanzi
Kunezici ezintathu:
(1) i-ionin, umsebenzi wayo oyinhloko ukuvimbela isimila
I-Vascular hyperplasia kanye nokunamathela phakathi kwamathumba;
(2) I-Cytotoxin, ngokuqondile
Isetshenziselwa ukubulala amaseli ngolwelwesi lwamangqamuzana omdlavuza;
(3) Ukwenza i-apoptosis.nini
Izakhiwo ezilwa nomdlavuza nazo zike zatholakala e-pit viper venom.U-Duan Tao et al wase-Guangxi Jian

I-cytotoxin I 3-H3 yahlukaniswa ubuthi be-agkistrodon halys futhi yakhuliswa nge-in vitro.
Umugqa weseli yomdlavuza wamaphaphu womuntu (A549), ulayini womdlavuza wesisu somuntu (BG C) kanye nolayini we-human nasopharyngeal carcinoma cell (KB)
Ukusebenzisa.UZhang Liang et al.kuhlukaniswe izingxenye ezimbili ezilwa nomdlavuza A ebuhlungwini be-Agkistrodon agkistrodon eningizimu ye-Anhui
I-CTX-6 ne-ACTX-8 zihlolwe ngokumelene nomugqa wamangqamuzana omdlavuza wamaphaphu womuntu (A 5 4)
9) Okuzwela kakhulu, nokuzinza okuhle kokushisa.U-Lei Danqing nabanye abavela ku-agkistrodon venom
Ingxenye ye-molecule encane ye-polypeptide K yahlukaniswa ne-allantoic membrane yenkukhu
Indima ye-angiogenesis inamandla okuba isebenze kakhulu ngokumelene ne-tumor angiogenesis
I-Peptide.U-Li Yingxin et al wafunda umphumela wengxenye ye-K kumaseli omdlavuza we-ovarian womuntu akhuliswe ku-vitro
Ukusabalala kohlobo lwe-A 277 80 kwavinjwa kakhulu, futhi umshini wawungenzeka.
Ihlotshaniswa ne-anti-cell adhesion kanye ne-apoptosis eyengayo.

4) Eminye imiphumela yomzimba
I-Agkistrodon poison nayo itholakale ithuthukisa i-microcirculation, yehlisa umfutho wegazi, futhi yehlise ukuphaphama
Imiphumela enobuthi.I-Linzhentao nabanye bahlukaniswa nobuthi be-agkistrodon ngokunwebeka
I-Microvascular, ingxenye yokunciphisa umfutho wegazi, indlela yayo yokusebenza ingase ihlotshaniswe nayo
Ivimbela ukuhlangana kweplatelet futhi ivimbele ukungena kwe-platelet calcium kanye nokuhlanganisa i-calcium, ngaleyo ndlela
Yehlisa ukugcwala kwe-calcium ion yamahhala ku-cytoplasm yeplatelet.Li Wande et al
Kwatholakala ukuthi i-agkistrodon viper venom yayinomphumela osheshayo we-postsynaptic kumsipha ozwelayo weselesele.
Okungenzeka (F -EPS P) kunomphumela ovimbelayo.U-Chen Xingzhi et al.uthole ukuthi ku
Amaseli we-He-la kanye namaseli e-TH P-1 we-Agkistrodon halys venom
Amaphesenti ama-tachyzoite angenwe yi-T. gondii anyuswe kakhulu.